Acid-Bath Stem-Cell Study Under Investigation
By David Cyranoski,
Nature
| 02. 17. 2014
A leading Japanese research institute has opened an investigation into a groundbreaking stem-cell study after concerns were raised about its credibility.
The RIKEN centre in Kobe announced on Friday that it is looking into alleged irregularities in the work of biologist Haruko Obokata, who works at the institution. She shot to fame last month as the lead author on two papers
1,
2 published in
Nature that demonstrated a simple way to reprogram mature mice cells into an embryonic state by simply applying stress, such as exposure to acid or physical pressure on cell membranes. The RIKEN investigation follows allegations on blog sites about the use of duplicated images in Obokata’s papers, and numerous failed attempts to replicate her results.
Cells in an embryonic state can turn into the various types of cells that make up the body, and are therefore an ideal source of patient-specific cells. They can be used to study the development of disease or the effectiveness of drugs and could also be transplanted to regenerate failing organs. A consistent and straightforward path to reprogramming...
Related Articles
By Annalee Armstrong, BioSpace | 09.11.2024
Complex gene therapies are starting to hit the market but all have faced the same reality: a tepid reception from the healthcare system and a cloudy path to profitability.
It can take about a year for a patient to go...
By Matthew Rozsa, Salon | 09.15.2024
When a person with a uterus decides to freeze their eggs, any number of things can go wrong. Ice crystal can form, killing an otherwise viable ovum. A fertilized egg may fail to properly implant, or the egg may...
By Sarah Kliff, The New York Times | 09.09.2024
Image by Stephen Andrews from Unsplash
Yale agreed on Monday to pay dozens of patients who had filed lawsuits claiming that they had endured excruciatingly painful egg retrieval procedures after a nurse at its fertility clinic secretly swapped their anesthesia...
By Ari Schulman, The New York Times | 09.09.2024
There was immediate backlash when Alabama’s Supreme Court ruled in February that embryos created through in vitro fertilization qualified as children under the state’s wrongful death law. But it was a backlash as much from the right as from the...