Test Is Improved Predictor of Fetal Disorders
By Pam Belluck,
New York Times
| 02. 26. 2014
A test that analyzes fetal DNA found in a pregnant woman’s blood proved much more accurate in screening for Down syndrome and another chromosomal disorder than the now-standard blood test, a new study has found. The promising results may change how prenatal screening for genetic diseases is done, though the test is costly and generally not yet covered by insurance for women at low risk.
The study, published on Wednesday in
The New England Journal of Medicine, found that the fetal DNA test was 10 times better in predicting cases of Down syndrome than the standard blood test and ultrasound screening, and five times better in predicting the other disorder, Trisomy 18. It also greatly reduced the number of false-positive results.
It could prevent many women who would otherwise get the standard blood test from needing to confirm positive results with invasive tests like amniocentesis or chorionic villus sampling, which can be stressful, much more costly and carry small risks of miscarriage. “Nine out of 10 women who are currently being referred for further testing would not need invasive...
Related Articles
By Matthew Rozsa, Salon | 09.15.2024
When a person with a uterus decides to freeze their eggs, any number of things can go wrong. Ice crystal can form, killing an otherwise viable ovum. A fertilized egg may fail to properly implant, or the egg may...
By Sarah Kliff, The New York Times | 09.09.2024
Image by Stephen Andrews from Unsplash
Yale agreed on Monday to pay dozens of patients who had filed lawsuits claiming that they had endured excruciatingly painful egg retrieval procedures after a nurse at its fertility clinic secretly swapped their anesthesia...
By Ari Schulman, The New York Times | 09.09.2024
There was immediate backlash when Alabama’s Supreme Court ruled in February that embryos created through in vitro fertilization qualified as children under the state’s wrongful death law. But it was a backlash as much from the right as from the...
By Megan Agnew, The Times | 09.15.2024
Faith Hartley always wanted two girls — a blonde and a redhead. “I thought, I’ll have one that looks like me,” says Hartley, 35, smoothing her golden hair in the Los Angeles valley home she shares with her husband, Neil...